{"_id":"598498f3679764002322db7e","project":"55faf11ba62ba1170021a9a7","version":{"_id":"55faf11ba62ba1170021a9aa","project":"55faf11ba62ba1170021a9a7","__v":38,"createdAt":"2015-09-17T16:58:03.490Z","releaseDate":"2015-09-17T16:58:03.490Z","categories":["55faf11ca62ba1170021a9ab","55faf8f4d0e22017005b8272","55faf91aa62ba1170021a9b5","55faf929a8a7770d00c2c0bd","55faf932a8a7770d00c2c0bf","55faf94b17b9d00d00969f47","55faf958d0e22017005b8274","55faf95fa8a7770d00c2c0c0","55faf96917b9d00d00969f48","55faf970a8a7770d00c2c0c1","55faf98c825d5f19001fa3a6","55faf99aa62ba1170021a9b8","55faf99fa62ba1170021a9b9","55faf9aa17b9d00d00969f49","55faf9b6a8a7770d00c2c0c3","55faf9bda62ba1170021a9ba","5604570090ee490d00440551","5637e8b2fbe1c50d008cb078","5649bb624fa1460d00780add","5671974d1b6b730d008b4823","5671979d60c8e70d006c9760","568e8eef70ca1f0d0035808e","56d0a2081ecc471500f1795e","56d4a0adde40c70b00823ea3","56d96b03dd90610b00270849","56fbb83d8f21c817002af880","573c811bee2b3b2200422be1","576bc92afb62dd20001cda85","5771811e27a5c20e00030dcd","5785191af3a10c0e009b75b0","57bdf84d5d48411900cd8dc0","57ff5c5dc135231700aed806","5804caf792398f0f00e77521","58458b4fba4f1c0f009692bb","586d3c287c6b5b2300c05055","58ef66d88646742f009a0216","58f5d52d7891630f00fe4e77","59a555bccdbd85001bfb1442"],"is_deprecated":false,"is_hidden":false,"is_beta":true,"is_stable":true,"codename":"","version_clean":"1.0.0","version":"1.0"},"category":{"_id":"58458b4fba4f1c0f009692bb","project":"55faf11ba62ba1170021a9a7","version":"55faf11ba62ba1170021a9aa","__v":0,"sync":{"url":"","isSync":false},"reference":false,"createdAt":"2016-12-05T15:44:15.650Z","from_sync":false,"order":6,"slug":"datasets-hub","title":"DATASETS HUB"},"user":"5613e4f8fdd08f2b00437620","__v":0,"parentDoc":null,"updates":[],"next":{"pages":[],"description":""},"createdAt":"2017-08-04T15:55:31.023Z","link_external":false,"link_url":"","githubsync":"","sync_unique":"","hidden":false,"api":{"results":{"codes":[]},"settings":"","auth":"required","params":[],"url":""},"isReference":false,"order":9,"body":"The [Therapeutically Applicable Research to Generate Effective Treatments (TARGET)](https://ocg.cancer.gov/programs/target/overview) dataset was generated by a diverse consortium of investigators to facilitate the discovery of genetic changes that underlie the development and progression of childhood cancers for which there currently are limited treatment options. The initiative is jointly managed within the [National Cancer Institute (NCI)](https://www.cancer.gov/) by the [Office of Cancer Genomics (OCG)](https://ocg.cancer.gov/) and the [Cancer Therapy Evaluation Program (CTEP)](https://ctep.cancer.gov/) and builds upon the resources of several other high-profile NCI cancer genomics programs, including [The Cancer Genome Atlas (TCGA)](https://cancergenome.nih.gov/), the [Cancer Genome Characterization Initiative (CGCI)](https://ocg.cancer.gov/programs/cgci), and the [Strategic Partnership to Evaluate Cancer Signatures (SPECS)](https://cdp.cancer.gov/scientific_programs/specs/default.htm). The majority of TARGET project teams are associated with the [Children’s Oncology Group (COG)](https://www.childrensoncologygroup.org/), an NCI clinical trials program that focuses exclusively on research into childhood and adolescent cancers.\n\nThe TARGET project first consisted of two pilot programs that generated genomic and transcriptomic data from patients with high-risk subtypes of acute lymphoblastic leukemia (ALL) and neuroblastoma (NBL). The [dataset](https://ocg.cancer.gov/programs/target/data-matrix) has since been expanded to encompass data collected using a variety of sequencing and array-based methods to examine the genomes, transcriptomes, and epigenomes of patients representing subtypes of acute myeloid leukemia, osteosarcoma, and select kidney tumors as well as additional subtypes of ALL and NBL.\n\nFor a full list of TARGET GRCh38 data available on the CGC, see the table below. The table details data categories and types, the data format of data subtypes, and the access level of each data type. Note that TARGET GRCh38 contains Open Data and Controlled Data. Learn more about [data access levels](doc:dbgap-controlled-data-access#data-access-levels).\n\nLearn more about the [metadata](doc:target-metadata) for the TARGET GRCh38 dataset.\n[block:image]\n{\n  \"images\": [\n    {\n      \"image\": [\n        \"https://files.readme.io/0c9fe10-Screen_Shot_2017-08-04_at_5.54.47_PM.png\",\n        \"Screen Shot 2017-08-04 at 5.54.47 PM.png\",\n        661,\n        483,\n        \"#464d63\"\n      ]\n    }\n  ]\n}\n[/block]","excerpt":"<a href=\"about-datasets\" style=\"color:#132c56\">ABOUT DATASETS</a> > TARGET data","slug":"target-data","type":"basic","title":"TARGET GRCh38 data"}

TARGET GRCh38 data

<a href="about-datasets" style="color:#132c56">ABOUT DATASETS</a> > TARGET data

The [Therapeutically Applicable Research to Generate Effective Treatments (TARGET)](https://ocg.cancer.gov/programs/target/overview) dataset was generated by a diverse consortium of investigators to facilitate the discovery of genetic changes that underlie the development and progression of childhood cancers for which there currently are limited treatment options. The initiative is jointly managed within the [National Cancer Institute (NCI)](https://www.cancer.gov/) by the [Office of Cancer Genomics (OCG)](https://ocg.cancer.gov/) and the [Cancer Therapy Evaluation Program (CTEP)](https://ctep.cancer.gov/) and builds upon the resources of several other high-profile NCI cancer genomics programs, including [The Cancer Genome Atlas (TCGA)](https://cancergenome.nih.gov/), the [Cancer Genome Characterization Initiative (CGCI)](https://ocg.cancer.gov/programs/cgci), and the [Strategic Partnership to Evaluate Cancer Signatures (SPECS)](https://cdp.cancer.gov/scientific_programs/specs/default.htm). The majority of TARGET project teams are associated with the [Children’s Oncology Group (COG)](https://www.childrensoncologygroup.org/), an NCI clinical trials program that focuses exclusively on research into childhood and adolescent cancers. The TARGET project first consisted of two pilot programs that generated genomic and transcriptomic data from patients with high-risk subtypes of acute lymphoblastic leukemia (ALL) and neuroblastoma (NBL). The [dataset](https://ocg.cancer.gov/programs/target/data-matrix) has since been expanded to encompass data collected using a variety of sequencing and array-based methods to examine the genomes, transcriptomes, and epigenomes of patients representing subtypes of acute myeloid leukemia, osteosarcoma, and select kidney tumors as well as additional subtypes of ALL and NBL. For a full list of TARGET GRCh38 data available on the CGC, see the table below. The table details data categories and types, the data format of data subtypes, and the access level of each data type. Note that TARGET GRCh38 contains Open Data and Controlled Data. Learn more about [data access levels](doc:dbgap-controlled-data-access#data-access-levels). Learn more about the [metadata](doc:target-metadata) for the TARGET GRCh38 dataset. [block:image] { "images": [ { "image": [ "https://files.readme.io/0c9fe10-Screen_Shot_2017-08-04_at_5.54.47_PM.png", "Screen Shot 2017-08-04 at 5.54.47 PM.png", 661, 483, "#464d63" ] } ] } [/block]